Pregabalin powder
Other names: Raw 3-isobutyl GABA powder
◐ Accept Customized Service
◐ Professional Manufacturer with Large Factory
◐ Production carried out under CGMP Regulation and Trackable
◐ ISO9001 & ISO14000
SHARE THIS
Get a Bulk quotation
If you need a larger quantity. Please fill in the form, our BD (Business Development) provides you with a competitive quotation.
Product Name: | Pregabalin powder |
CAS number: | 148553-50-8 |
Molecular Formula: | C8H17NO2 |
Molecular Weight: | 159.23 |
Melt Point: | 194-196°C |
Purity: | >98% |
Appearance: | White off-white crystalline powder |
Storage Temp: | RT |
Noted: Please refer to Certificate of Analysis for more information of pregabalin powder.
( 16 5 12 )↗
PubMed Central
Highly respected database from the National Institutes of Health
Go to source
1.What Is Pregabalin Powder?
Pregabalin powder is a widely used medication primarily indicated for the treatment of several conditions, including neuropathic pain, epilepsy, fibromyalgia, and generalized anxiety disorder. It comes in capsule form for oral administration, and it’s important to take it exactly as prescribed by your healthcare provider. Pregabalin affects the nerves and brain chemicals that play a role in seizures and pain signals.
Pregabalin powder offers numerous benefits, including effective pain management, seizure control, anxiety relief, improved absorption, customizable dosing, ease of administration, reduced adverse effects, potential cost savings, and formulation versatility. These advantages make it a valuable option for patients and healthcare providers in managing a range of medical conditions.
2.How Does Pregabalin Powder Works?
Mechanism of Action
Pregabalin is an anticonvulsant and neuropathic pain agent that works by affecting certain neurotransmitters in the brain. Specifically, it binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding inhibits excitatory neurotransmitter release, which helps to stabilize neuronal activity and reduce pain signals and seizures.
Indications
Neuropathic Pain: Pregabalin is effective in managing pain caused by nerve damage, which can result from conditions like diabetes (diabetic neuropathy), shingles (postherpetic neuralgia), or spinal cord injury.
Epilepsy: It is used as an adjunctive therapy for partial seizures with or without secondary generalization in adults.
Fibromyalgia: Pregabalin can help reduce the widespread pain and tenderness associated with fibromyalgia.
Generalized Anxiety Disorder (GAD): It is also prescribed to alleviate symptoms of GAD.
3.The Benefits of Pregabalin Powder
①Effective Pain Management
Pregabalin is widely used for its analgesic properties, particularly in neuropathic pain conditions. It is effective in managing pain associated with diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. The powder form can be easily adjusted for precise dosing, which is beneficial for pain management.
②Seizure Control
Pregabalin is also an anticonvulsant and is used as an adjunctive therapy for partial-onset seizures in adults. The powder form allows for flexible dosing adjustments that can be critical in managing epilepsy.
③Anxiety Relief
Pregabalin has anxiolytic effects and is used to treat generalized anxiety disorder (GAD). The powder form can provide a rapid onset of action when formulated correctly, offering timely relief for anxiety symptoms.
④Improved Absorption and Bioavailability
The powder form of pregabalin may enhance absorption and bioavailability compared to traditional tablet forms. This can lead to more effective and quicker symptom relief.
⑤Customization of Dosage
For patients who require specific dosages that are not available in standard tablet or capsule forms, pregabalin powder can be precisely measured to provide the exact dose needed. This is particularly useful for patients with unique dosing requirements or those with sensitivity to certain dosages.
⑥Ease of Administration
Pregabalin powder can be mixed with food or liquid, making it easier to administer for individuals who have difficulty swallowing pills. This can improve adherence to medication regimens, especially in elderly patients or those with dysphagia.
⑦Reduced Risk of Adverse Effects
By allowing for precise dosing and potentially improved bioavailability, the powder form of pregabalin can help minimize the risk of adverse effects that might occur with incorrect dosing or poor absorption.
⑧Potential for Lower Cost
In some cases, pregabalin powder may be more cost-effective than branded capsule or tablet forms, especially for compounding pharmacies that prepare individualized doses for patients.
⑨Versatility in Formulation
The powder form can be used to create various formulations, such as topical preparations, which can be used for localized pain relief, expanding the range of conditions that pregabalin can effectively treat.
4.The Dosage of Pregabalin Powder
Pregabalin is available in capsule form and is taken orally. It’s essential to follow the dosage and administration instructions provided by a healthcare provider, as improper use can lead to increased side effects or reduced efficacy.
The dosage of pregabalin varies depending on the condition being treated:
Neuropathic Pain: Typically, the starting dose is 75 mg twice daily, which can be increased based on efficacy and tolerability.
Epilepsy: The dose often starts at 150 mg per day, divided into two or three doses, with potential adjustments as needed.
Fibromyalgia: Commonly begins at 75 mg twice daily, with the possibility of increasing to 150 mg twice daily.
GAD: The initial dose is usually 150 mg per day, divided into doses, which can be increased if necessary.
( 12 15 23 )↗
PubMed Central
Highly respected database from the National Institutes of Health
Go to source
5.What are the Side Effects of Pregabalin Powder?
- Common Side Effects:Dizziness, somnolence, dry mouth, edema, blurred vision, weight gain.
- Serious Side Effects:Allergic reactions, mood changes, muscle pain, and unexplained bruising or bleeding.
Pregabalin powder is a medication used to treat neuropathic pain, epilepsy, fibromyalgia, and generalized anxiety disorder. Adherence to the prescribed regimen and regular consultations with a healthcare provider can help optimize its benefits while minimizing potential risks. Always discuss any concerns or side effects with a healthcare professional to ensure safe and effective use of pregabalin.
6.Precautions and Interactions for Pregabalin Powder
- Pregabalin should be used with caution in individuals with a history of substance abuse, as it has potential for dependence.
- It can interact with other medications, so it’s important to inform the healthcare provider of all drugs being taken, including over-the-counter medications and supplements.
- Abrupt discontinuation of pregabalin should be avoided, as it can lead to withdrawal symptoms. It should be tapered off gradually under the guidance of a healthcare provider.
7.Where to Buy Pregabalin Powder?
In the pharmaceutical industry, pregabalin powder is a critical raw material used to create the final pharmaceutical products. It is measured and processed under strict quality control standards to ensure the correct dosage and efficacy of the medication.
In summary, pregabalin powder is the raw, unprocessed form of the medication used to treat various neurological and pain-related conditions, and it plays a crucial role in the manufacturing of pregabalin capsules and tablets.
Aea.ltd is one of the most well-known manufacturers and suppliers of pregabalin powder, which is committed to providing high-quality, pure pregabalin powder to customers around the world. Besides, Aea.ltd has a team of experienced professionals to ensure that all our products meet the highest standards of quality and purity. Moreover, Aea.ltd uses advanced technology and equipment to manufacture pregabalin powder that is free from impurities and contaminants. Finally, Aea.ltd has a strict quality control process in place to ensure that every batch of pregabalin powder is thoroughly tested for purity and potency.
8.FAQ
①What is the strongest drug for nerve pain?
Anticonvulsants are one of the most effective medications for treating nerve pain. Examples include pregabalin (Lyrica) and gabapentin (Neurontin). These medications are typically very effective in treating nerve pain, but they may also cause undesired side effects, such as: lethargy.
②Is pregabalin a strong pain killer?
Pain was reduced by a third or more for 5 in 10 with pregabalin 300 mg or 600 mg daily, and 3 in 10 with placebo. For pain caused by diabetes, 3 or 4 in 10 people had pain reduced by half or more with pregabalin 300 mg or 600 mg daily, and 2 or 3 in 10 with placebo.
③How long can you take pregabalin for nerve pain?
If you have epilepsy, it’s likely that once your condition is under control you will continue to take pregabalin for many years. If you’re taking pregabalin for nerve pain or anxiety it’s likely that once your symptoms have gone you will continue to take it for several months to stop them coming back.
④Is pregabalin good for anxiety?
Pregabalin is an anticonvulsant drug which is sometimes used as an anti-anxiety medication. It is also known by the trade names Alzain, Axalid, Lecaent and Lyrica. It is a class C controlled medicine.
⑤Is pregabalin good for sleep?
Pregabalin is a novel anticonvulsant drug, and has also been reported effective in improving sleep quality in patients who suffer from other diseases. Study Impact: We can consider pregabalin as a candidate for withdrawal from hypnotics and improved sleep in patients with hypnotic-dependent insomnia.
( 15 5 12 )↗
PubMed Central
Highly respected database from the National Institutes of Health
Go to source
Are you looking for the best Pregabalin powder manufacturer? You are here in the right place. Aea.ltd is a reliable and professional Pregabalin powder manufacturer in the maket, you will get best quality Prebagalin powder in competitive factory price here.
Pregabalin pure powder is white colour, it was designed as a more potent successor to gabapentin, and sold under the name Lyrica. Pregabalin is an anticonvulsant drug used for neuropathic pain.
Aea.ltd as the best Pregabalin powder manufacturer, produce Pregabalin powder according to cGMP standard strictly, equipped with HPLC, GC, and other analytical instruments. Tests can be done on IR, GC/MS, LC/MS and 400NMR at the SIOC through contract. Our factory have 3×1000KG standard Pregabalin powder production reactors, monthly synthetic production capacity reach 1350KG. QA Operations have been in place for several years to insure that products at our company are prepared responsibly and in accordance with ISO 9001 standards.
If you are looking for the best pregabalin powder, Aea.ltd is a one stop reliable pregabalin powder manufacturer offering you the best quality Pregabalin pure powder from grams to kilograms, and other steroids powder, directly to your address in safe and secure local delivery service.
Place your order to get the pure Pregabalin powder from this top Pregabalin powder manufacturer. You will get professional support, no matter shipping or package, quality is always the first important!
( 12 15 7 )↗
PubMed Central
Highly respected database from the National Institutes of Health
Go to source
Aea.ltd is the professional manufacturer of pregabalin powder and the production capacity is stable. Our factory will confirm the quality standard before sell, make sure that all pregabalin powder which sell to clients is conform the quality standard. We also welcome our clients to test our pure pregabalin raw powder at anytime. Here are some testing reports of pregabalin powder for reference:
1.Certificate of Analysis-Pregabalin Powder
COA-Pregabalin Powder(CAS 148553-50-8)
What is COA and What does COA tell you?
A certificate of analysis (CoA) is an essential document in chemical distribution that outlines all the tests performed on a product before it is shipped to a customer. The Certificate of Analysis (CoA) is a contractual document most often issued by a quality control department. It serves to confirm with evidence (analysis results) that a product is tested according to certain standards and methods, and that test results are available.
2.HNMR Report-Pregabalin Powder
What is HNMR and What does HNMR tell you?
H Nuclear Magnetic Resonance (NMR) spectroscopy is an analytical chemistry technique used in quality control and research for determining the content and purity of a sample as well as its molecular structure. For example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR can either be used to match against spectral libraries or to infer the basic structure directly. Once the basic structure is known, NMR can be used to determine molecular conformation in solution as well as studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion.
( 14 17 2 )↗
PubMed Central
Highly respected database from the National Institutes of Health
Go to source
Aea.ltd is professional manufacturer of the best pregabalin powder and our factory produce high quality pregabalin powder in term, we welcomes many requesters and buyers of pure pregabalin bulk powder to contact us! Individual users should avoid buying bulk pregabalin powder. The advantages of wholesale pregabalin bulk powder from Aea.ltd include:
❶Factory production on a large scale, consistent supply, a short delivery cycle, and highprice competitiveness;
❷Provide a quality assurance report for the corresponding batch of quality test report.
❸Professional logistics customization solutions, on-time delivery;
❹Payment methods that are diverse, such as TT and virtual currency;
❺High-quality pre-sales and after-sales service, followed by product and order details consultation.
1.How to get the quick quote of pregabalin powder online?
Visit professional pregabalin powder supplier-Aea.ltd website,choose the pregabalin powder you want,and leave your contact and message on Aea.ltd wbsite,then submit,Aea.ltd, the customer service will reply you in 12 hours once received your message,then talk in details.
2.Does Aea.ltd support the free sample of pregabalin powder?
It depends, different products with different policy, please check it with our customer service. Most of products can be accepted for free sample. Welcome our clients test our pregabalin powder at any time!
3.Can I buy discount pregabalin lyrica powder from Aea.ltd?
Sure, our factory produce high quality pregabalin powder in term and keep pregabalin powder in stock. Our company has planned promotions on bulk pregabalin powder every year. You can buy high quality pregabalin powder by lower price during promotion sale. You can keep touch with our customer manager and they will update the latest pregabalin powder price for you in time.
( 4 17 2 )↗
PubMed Central
Highly respected database from the National Institutes of Health
Go to source
You Might Also Be Concerned About These Issues:
1. How to take prehabalin? And dosage? |
2. How long can you take pregabalin for? |
3. How to find best pregabalin powder suppliers online? |
4. Is pregabalin good for sleep? |
5. Is pregabalin legal or illegal? |
6. How can I get 99% China pregabalin powder? |
7. Why is pregabalin a Class C drug? |
8. What is the best time to take pregabalin? |
9. Is it true that all pregabalin bulk powder suppliers provide free samples? |
10. How fast is pregabalin absorbed? |
11. Where to buy cheap pregabalin powder in USA? |
As for these questions, please go to the offical website of original drug and see full Prescribing Information and Medication Guide, especially for personal use, please use pregabalin under the guide of doctor.
( 12 5 1 )↗
PubMed Central
Highly respected database from the National Institutes of Health
Go to source
[1] Dworkin RH, O’Connor AB, Backonja M, et al. Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain 2007;132:237-51.
[2] Finnerup NB, Jensen TS. Clinical use of pregabalin in the management of central neuropathic pain. Neuropsychiatric Disease and Treatment 2007;3:885-91.
[3] Kalso E, Aldington DJ, Moore RA. Drugs for neuropathic pain. BMJ 2013;347:f7339.
[4] Mannix, Liam (December 18, 2018). “This popular drug is linked to addiction and suicide. Why do doctors keep prescribing it?”. The Canberra Times. Archived from the original on December 18, 2018. Retrieved December 18, 2018.
[5] Wheless, James W.; Willmore, James; Brumback, Roger A. (2009). Advanced Therapy in Epilepsy. PMPH-USA. p. 302. ISBN 978-1-60795-004-2.
( 12 13 21 )↗
PubMed Central
Highly respected database from the National Institutes of Health
Go to source
[cusrev_reviews]